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Extended space missions will necessitate that life support subsystems operate on a closed ecological or bioregenerating principle. This entails a continual recycling or regeneration of materials to sustain space crews.

Potable water may be made available by a variety of techniques from various sources, such as urine and atmospheric condensate. Microbiological potability standards that can realistically be applied to space water supplies are dictated by the inherent technological problems and logistic limitations.

With these in mind, a standard of sterility is proposed and the reasons for this stringent requirement are indicated. For ground based studies, a less stringent standard is also compatible with equipment capabilities and experimental requirements.

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